Misdorp W
Vakgroepen Pathologie en Ziekten van Gezelschapsdieren, Faculteit der Diergeneeskunde, Universiteit van Utrecht, Nederland.
Tijdschr Diergeneeskd. 1994 Dec 1;119(23):729-34.
A review of research in veterinary oncology, as executed in Amsterdam and Utrecht, is presented. Also an inquiry into the cooperation between oncologist, pathologist and practitioner is discussed. It is concluded that microscopic tumour diagnosis is practized at too low a scale (+/- 30%). Veterinary oncology has significance both from the veterinary and the comparative (model) point of view. Etiologic-pathogenetic and biologic-therapeutic aspects are studied in a multidisciplinary way. Intercellular communication, growth factors and intercellular matrix are items of present and future research. Molecular-genetic research is in progress. Prevention of mammary tumours by ovariectomy (dog, cat) and of malignant lymphoma (cat) by fighting FeLV seems promising.
本文对在阿姆斯特丹和乌得勒支开展的兽医肿瘤学研究进行了综述。同时还讨论了肿瘤学家、病理学家和从业者之间的合作情况。得出的结论是,微观肿瘤诊断的实施规模过低(约30%)。兽医肿瘤学从兽医和比较(模型)的角度来看都具有重要意义。病因-发病机制和生物-治疗方面正在以多学科方式进行研究。细胞间通讯、生长因子和细胞间基质是当前和未来研究的课题。分子遗传学研究正在进行中。通过卵巢切除术预防犬猫乳腺肿瘤以及通过对抗猫白血病病毒预防猫恶性淋巴瘤似乎很有前景。