Nguyen S M, Thamm D H, Vail D M, London C A
Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA.
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Vet Comp Oncol. 2015 Sep;13(3):176-83. doi: 10.1111/vco.12032. Epub 2013 Mar 28.
In veterinary medical oncology, there is currently no standardized protocol for assessing response to therapy in solid tumours. The lack of such a formalized guideline makes it challenging to critically compare outcome measures across various treatment protocols. The Veterinary Cooperative Oncology Group (VCOG) membership consensus document presented here is based on the recommendations of a subcommittee of American College of Veterinary Internal Medicine (ACVIM) board-certified veterinary oncologists. This consensus paper has used the human response evaluation criteria in solid tumours (RECIST v1.1) as a framework to establish standard procedures for response assessment in canine solid tumours that is meant to be easy to use, repeatable and applicable across a variety of clinical trial structures in veterinary oncology. It is hoped that this new canine RECIST (cRECIST v1.0) will be adopted within the veterinary oncology community and thereby facilitate the comparison of current and future treatment protocols used for companion animals with cancer.
在兽医肿瘤学领域，目前尚无用于评估实体瘤治疗反应的标准化方案。缺乏这样一个正式的指南使得严格比较各种治疗方案的结果指标具有挑战性。此处呈现的兽医合作肿瘤学小组（VCOG）成员共识文件基于美国兽医内科学会（ACVIM）董事会认证的兽医肿瘤学家小组委员会的建议。这份共识文件以人类实体瘤反应评估标准（RECIST v1.1）为框架，建立了犬类实体瘤反应评估的标准程序，旨在易于使用、可重复且适用于兽医肿瘤学的各种临床试验结构。希望这个新的犬类RECIST（cRECIST v1.0）能在兽医肿瘤学界得到采用，从而便于比较目前及未来用于患癌伴侣动物的治疗方案。
