Christensen M F
Herning Centralsygehus, børneafdelingen.
Ugeskr Laeger. 1994 Aug 15;156(33):4713-5.
Suggestions in the literature about a possible role of hypersensitivity in children with recurrent abdominal pain induced an open controlled investigation in twenty children with recurrent abdominal pain and in twenty healthy children. The purpose was to look for differences in the numbers of hypersensitivity markers in pain and control children. Hypersensitivity markers were defined in four areas: familial disposition to atopic disease, atopic disease in the child's history, atopic disease disclosed at a clinical examination, and elevated levels of blood eosinophils and serum immunoglobulin E antibodies to selected inhalant allergens and food allergens. In no child was abdominal pain provoked by specific food intake. The total number of markers in the pain children was 21, and in the control children 31. In spite of the small material it thus seems unlikely that hypersensitivity plays an influential part in the etiology of children's recurrent abdominal pain.
文献中关于超敏反应在复发性腹痛儿童中可能起的作用的建议，促使对20名复发性腹痛儿童和20名健康儿童进行了一项开放对照研究。目的是寻找疼痛儿童和对照儿童中超敏反应标志物数量的差异。超敏反应标志物在四个方面进行定义：特应性疾病的家族倾向、儿童病史中的特应性疾病、临床检查中发现的特应性疾病，以及血液嗜酸性粒细胞水平升高和针对选定吸入性过敏原和食物过敏原的血清免疫球蛋白E抗体水平升高。没有一名儿童因特定食物摄入而引发腹痛。疼痛儿童的标志物总数为21个，对照儿童为31个。尽管样本量较小，但超敏反应似乎不太可能在儿童复发性腹痛的病因中起重要作用。
