Solokhin E V, Pchelintsev S Iu, Iurov S V, Uraeva V I, Afanas'ev S S, Vorob'ev A A
Zh Mikrobiol Epidemiol Immunobiol. 1994 Jul-Aug(4):42-5.
The activity of NK and K cells in mice immunized against plague has been studied. This activity has been shown to depend on the dose of the vaccine and the time elapsed after immunization. The booster immunization of mice leads to an increase in the specific sensitization of lymphocytes, the antibody level and to an increase in the activity of killer cells. Changes in the cytotoxicity of NK cells on days 21-28 after primary and booster immunization are considered to occur not due to the action of Yersinia pestis themselves, but as the result of the immunological transformation induced by these microorganisms in the animals.
对免疫鼠疫的小鼠体内自然杀伤细胞（NK细胞）和杀伤细胞（K细胞）的活性进行了研究。结果表明，这种活性取决于疫苗剂量和免疫后经过的时间。对小鼠进行加强免疫会导致淋巴细胞特异性致敏、抗体水平升高以及杀伤细胞活性增强。初次免疫和加强免疫后第21至28天，NK细胞细胞毒性的变化被认为并非是鼠疫耶尔森菌本身作用的结果，而是这些微生物在动物体内诱导的免疫转化的结果。
