Sasaki E, Nakatani T, Taenaka Y, Takano H, Hirose H
Department of Artificial Organs, National Cardiovascular Center Research Institute, Osaka, Japan.
Artif Organs. 1994 Aug;18(8):603-10. doi: 10.1111/j.1525-1594.1994.tb03385.x.
A novel real-time volumetric method was developed for a pulsatile pump. This method, the impedance method, used electrical impedance change in the blood chamber according to volume change while pumping. This method was evaluated with two kinds of air-driven diaphragm pumps. During in vitro tests, the impedance method indicated real-time volume change, and there was excellent correlation between computed stroke volume with the impedance method and measured stroke volume with the electromagnetic flowmeter. In chronic animal tests with goats and in a clinical case, the impedance method measured pump output accurately, and it detected diaphragm motion in real-time. In addition, excellent durability was seen. Full-fill to full-empty drive was realized accurately with this method. Application of the impedance method was easy, and it did not deteriorate native antithrombogencity of the pump. The impedance method is practical and useful to estimate the pumping condition of a pulsatile blood pump, especially a diaphragm pump. This method would be useful in clinical application.
为一种脉动泵开发了一种新型实时容积测量方法。这种方法即阻抗法，利用泵血时血腔中因容积变化而产生的电阻抗变化。使用两种气动隔膜泵对该方法进行了评估。在体外测试中，阻抗法显示了实时容积变化，并且用阻抗法计算的每搏输出量与用电磁流量计测量的每搏输出量之间存在极好的相关性。在山羊的慢性动物试验和一个临床病例中，阻抗法准确测量了泵的输出量，并且实时检测到了隔膜运动。此外，还观察到了出色的耐用性。用这种方法准确实现了从完全充盈到完全排空的驱动。阻抗法应用简便，且不会降低泵的固有抗血栓形成能力。阻抗法对于评估脉动血泵尤其是隔膜泵的泵血状况是实用且有用的。该方法在临床应用中会很有用。
