Fernández-Teruel A, Escorihuela R M, Driscoll P, Tobeña A, Bättig K
Department of Pharmacology and Psychiatry, School of Medicine, Autonomous University of Barcelona, Spain.
Behav Genet. 1994 Sep;24(5):419-25. doi: 10.1007/BF01076177.
Two hundred forty 30-day-old Roman high- and low-avoidance (RHA/Verh and RLA/Verh) rats (divided equally by line and gender) which had received several peri- and/or postnatal treatments, forming two factorial [line x sex x treatment(s)] experimental designs, were tested in a hexagonal tunnel maze including a brightly illuminated central arena. The present study reports the results of correlational and factorial (principal-components) analyses performed on the data from those two experimental constituencies. The purpose of the study was to evaluate the validity of the hexagonal tunnel maze for testing emotionality, and therefore, the following measures were included in the analysis: entries into the central illuminated arena, total activity during testing, defecation during testing, and defecation during handling and weighing after testing. An overall pattern of negative correlations (or opposite loadings in the principal-components analyses) between defecation (especially during maze testing) and entries into the illuminated center and activity was found, thus giving support to the validity of entries into the illuminated center as being indicative of emotional reactivity.
240只30日龄的罗马高回避和低回避（RHA/Verh和RLA/Verh）大鼠（按品系和性别平均分配）接受了几种围产期和/或产后处理，形成了两个析因[品系×性别×处理（多个）]实验设计，在一个包括明亮照明中央区域的六边形隧道迷宫中进行测试。本研究报告了对这两个实验群体的数据进行相关分析和析因（主成分）分析的结果。该研究的目的是评估六边形隧道迷宫用于测试情绪性的有效性，因此，分析中纳入了以下测量指标：进入中央照明区域的次数、测试期间的总活动量、测试期间的排便量以及测试后处理和称重期间的排便量。发现排便（尤其是在迷宫测试期间）与进入照明中心的次数和活动量之间存在负相关的总体模式（或在主成分分析中呈相反载荷），从而支持了进入照明中心的次数作为情绪反应指标的有效性。
