多血管炎重叠综合征：与结节性多动脉炎相关的皮肤白细胞破碎性血管炎。
Polyangiitis overlap syndrome: cutaneous leukocytoclastic vasculitis associated with polyarteritis nodosa.
作者信息
Park C K, Ko Y H, Park M H, Lee J D, Lee C W
机构信息
Department of Pathology, College of Medicine, Han Yang University, Seoul, Korea.
出版信息
J Korean Med Sci. 1994 Jun;9(3):243-7. doi: 10.3346/jkms.1994.9.3.243.
A rare case of polyangiitis overlap syndrome is described. The patient was a 25-year-old man who had palpable purpura on his legs which showed leukocytoclastic vasculitis, and polyarteritis nodosa. Superior mesenteric arteriography showed microaneurysms in jejunal branches with focal segmental necrotizing arteritis of small and medium sized muscular arteries in the jejunum. Deposits of IgA and C3 in the superficial blood vessels of the lesional skin were consistent with the features of Henoch-Schönlein purpura. The patient died about two months after initial admission in spite of cytotoxic agent and steroid administration.
本文描述了一例罕见的多血管炎重叠综合征病例。患者为一名25岁男性，双下肢出现可触及的紫癜，表现为白细胞破碎性血管炎和结节性多动脉炎。肠系膜上动脉造影显示空肠分支有微动脉瘤，空肠中小肌性动脉有局灶性节段性坏死性动脉炎。病变皮肤浅表血管中IgA和C3的沉积符合过敏性紫癜的特征。尽管给予了细胞毒性药物和类固醇治疗，患者在初次入院后约两个月死亡。
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