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主动脉瓣置换术后主动脉夹层:发生率及对治疗策略的影响

Aortic dissection after aortic valve replacement: incidence and consequences for strategy.

作者信息

Prenger K, Pieters F, Cheriex E

机构信息

Department of Cardiothoracic Surgery, University Hospital Maastricht, The Netherlands.

出版信息

J Card Surg. 1994 Sep;9(5):495-8; discussion 498-9. doi: 10.1111/j.1540-8191.1994.tb00882.x.

DOI:10.1111/j.1540-8191.1994.tb00882.x
PMID:7994092
Abstract

From 1986 to 1994, 10 patients were observed to have developed an acute aortic dissection at some stage after an aortic valve replacement (AVR). Study of the characteristics of these patients showed that all patients had an aortic diameter of 50 mm or more (range 50 to 80 mm, mean 64 mm), and 70% suffered from systemic hypertension. Subsequently, the echocardiographic database, containing data from 33,105 studies in 21,484 patients, was searched for cases of AVR in which an accurate aortic dimension could be measured. Of 524 patients who had undergone AVR, an accurate aortic diameter was recorded in 419. Thirty-seven patients had an aortic size greater than 50 mm. All acute dissections occurred in this group of patients. The incidence of acute dissections among patients with significant aortic dilatation following AVR was 27%, whereas the overall incidence of acute dissection after AVR is 0.6%. Although there was a preponderance of tilting disc mechanical valves in the dissecting patients, the type of valve implanted does not seem to be of any importance. From these observations, we conclude that implantation of a valved conduit is indicated even in the presence of mild annuloaortic ectasia (aortic size = 50 mm). Patients who have had an AVR and show an enlarging aortic diameter exceeding 50 mm should have an elective reoperation at an early stage, especially when systemic hypertension is present.

摘要

1986年至1994年期间,观察到10例患者在主动脉瓣置换术(AVR)后的某个阶段发生了急性主动脉夹层。对这些患者的特征研究表明,所有患者的主动脉直径均在50mm或以上(范围为50至80mm,平均64mm),70%的患者患有系统性高血压。随后,在包含21484例患者的33105项研究数据的超声心动图数据库中搜索能够测量准确主动脉尺寸的AVR病例。在524例行AVR的患者中,419例记录了准确的主动脉直径。37例患者的主动脉尺寸大于50mm。所有急性夹层均发生在这组患者中。AVR后主动脉显著扩张的患者中急性夹层的发生率为27%,而AVR后急性夹层总的发生率为0.6%。尽管夹层患者中倾斜盘式机械瓣膜占多数,但植入瓣膜的类型似乎并不重要。根据这些观察结果,我们得出结论,即使存在轻度主动脉瓣环扩张(主动脉尺寸 = 50mm)也应植入带瓣管道。行AVR且主动脉直径增大超过50mm的患者应尽早进行择期再次手术,尤其是存在系统性高血压时。

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