Pavlin C J, Macken P, Trope G, Feldman F, Harasiewicz K, Foster F S
Department of Ophthalmology, Princess Margaret Hospital, Toronto, Ont.
Can J Ophthalmol. 1994 Aug;29(4):187-92.
We have developed a device capable of producing subsurface images in eyes at microscopic resolution. We call this method "ultrasound biomicroscopy." We examined 19 patients with pigmentary glaucoma or pigmentary dispersion syndrome using ultrasound biomicroscopy. Ten patients were found to have concave irides with small distances between the back of the iris and the zonule. In these patients iris-lens contact was greater than in patients without iris concavity and healthy patients. Nine patients did not show iris concavity or increased iris-lens contact. The finding of iris concavity and increased iris-lens contact is compatible with a theory of reverse pupil block producing intermittent iris-zonule touch, with a valve effect preventing posterior flow of aqueous. This theory was supported by the loss of concavity following iridotomy in three patients. The force that produces a reversal of the normal pressure gradient remains unclear, but recent evidence suggests that accommodation plays a major role. The patients who did not show iris concavity and increased iris-lens contact may have been examined at a time when these forces were not acting or had ceased to act.
我们研发了一种能够以微观分辨率生成眼部亚表面图像的设备。我们将这种方法称为“超声生物显微镜检查法”。我们使用超声生物显微镜检查法对19例色素性青光眼或色素播散综合征患者进行了检查。发现10例患者的虹膜呈凹形，虹膜后部与小带之间的距离较小。在这些患者中，虹膜与晶状体的接触比没有虹膜凹陷的患者及健康患者更紧密。9例患者未表现出虹膜凹陷或虹膜与晶状体接触增加。虹膜凹陷和虹膜与晶状体接触增加这一发现与反向瞳孔阻滞理论相符，该理论认为反向瞳孔阻滞会产生间歇性虹膜-小带接触，并具有阻止房水向后流动的瓣膜效应。三名患者在虹膜切开术后凹陷消失，这一理论得到了该现象的支持。产生正常压力梯度逆转的力量尚不清楚，但最近的证据表明调节起着主要作用。未表现出虹膜凹陷和虹膜与晶状体接触增加的患者，可能是在这些力量未起作用或已经停止作用的时候接受检查的。
