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安大略省子宫切除率的差异:指征重要吗?

Variations in hysterectomy rates in Ontario: does the indication matter?

作者信息

Hall R E, Cohen M M

机构信息

Institute for Clinical Evaluative Sciences in Ontario, North York.

出版信息

CMAJ. 1994 Dec 15;151(12):1713-9.

Abstract

OBJECTIVES

To examine variations in rates of hysterectomy for the five main indications for the procedure in regions of Ontario.

DESIGN

Cross-sectional population-based analysis of hospital discharge abstracts.

SETTING

All acute care facilities in Ontario.

PARTICIPANTS

All 65,599 women whose hospital record contained a procedure code indicating that a hysterectomy was performed between Apr. 1, 1988, and Mar. 31, 1991. Duplicate cases, records of cancelled procedures and nonresidents were excluded.

MAIN OUTCOME MEASURES

Crude and age-adjusted rates of hysterectomy, by indication, for each region of Ontario.

RESULTS

Five indications accounted for more than 80% of hysterectomies performed. The median age-adjusted rate of hysterectomy for Ontario regions during the study period was 6.25 per 1000 women, with a 2.7-fold variation among regions. The regions with rates of hysterectomy in the highest quartile tended to be rural, and those with rates in the lowest quartile tended to be urban areas with teaching hospitals. When rates of hysterectomy for specific indications were examined, they showed substantial variations among regions in the rate of the procedure for menstrual hemorrhage (18-fold variation), uterine prolapse (9.3-fold) and endometriosis (6.3-fold). A smaller but still significant variation was shown in the rate of hysterectomy for leiomyoma (2.3-fold). Regional variation in the rate of hysterectomy for cancer (2.5-fold) was not statistically significant.

CONCLUSIONS

There are large interregional variations in rates of hysterectomy, especially for indications that are more discretionary than others (i.e., menstrual hemorrhage, uterine prolapse and endometriosis) and less variation in rates when treatment options and diagnosis are clear-cut. This result suggests the need for more definitive practice guidelines on treatment of the indications for which the rate is more variable.

摘要

目的

研究安大略省各地区因子宫切除术的五个主要指征而进行该手术的比率差异。

设计

基于人群的医院出院摘要横断面分析。

地点

安大略省所有急性护理机构。

参与者

所有65599名女性,其医院记录包含表明在1988年4月1日至1991年3月31日期间进行了子宫切除术的手术代码。重复病例、取消手术记录和非居民被排除在外。

主要观察指标

安大略省各地区按指征划分的子宫切除术的粗率和年龄调整率。

结果

五个指征占所进行子宫切除术的80%以上。研究期间安大略省各地区子宫切除术的年龄调整率中位数为每1000名女性6.25例,各地区之间存在2.7倍的差异。子宫切除率处于最高四分位数的地区往往是农村地区,而处于最低四分位数的地区往往是有教学医院的城市地区。当检查特定指征的子宫切除率时,发现各地区在月经出血(18倍差异)、子宫脱垂(9.3倍)和子宫内膜异位症(6.3倍)手术率方面存在很大差异。子宫肌瘤的子宫切除率差异较小但仍显著(2.3倍)。癌症子宫切除率的地区差异(2.5倍)无统计学意义。

结论

子宫切除术的比率存在很大的地区间差异,特别是对于比其他指征更具可选择性的指征(即月经出血、子宫脱垂和子宫内膜异位症),而当治疗选择和诊断明确时,比率差异较小。这一结果表明,对于比率变化较大的指征,需要更明确的治疗实践指南。

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本文引用的文献

2
Indications for hysterectomy.子宫切除术的适应症。
N Engl J Med. 1993 Mar 25;328(12):856-60. doi: 10.1056/NEJM199303253281207.
3
Endometriosis.子宫内膜异位症
N Engl J Med. 1993 Jun 17;328(24):1759-69. doi: 10.1056/NEJM199306173282407.
6
Variations in medical care among small areas.小区域间医疗服务的差异。
Sci Am. 1982 Apr;246(4):120-34. doi: 10.1038/scientificamerican0482-120.
7
Small area statistics: large statistical problems.小区域统计:重大统计问题。
Am J Public Health. 1984 Apr;74(4):313-4. doi: 10.2105/ajph.74.4.313.
8
Dealing with medical practice variations: a proposal for action.应对医疗实践差异:行动建议
Health Aff (Millwood). 1984 Summer;3(2):6-32. doi: 10.1377/hlthaff.3.2.6.
10
Hysterectomy in the United States, 1965-84.1965 - 1984年美国的子宫切除术
Am J Public Health. 1988 Jul;78(7):852-3. doi: 10.2105/ajph.78.7.852.

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