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[通过流式细胞术研究胸腔积液中细胞的相对DNA含量及周期分布]

[Relative DNA content and cycle distribution of cells in pleural effusions studied by flow-cytometry].

作者信息

Shen C, Ye Y Q, Lou W T

机构信息

Chang Zheng Hospital, Second Military Medical University, PLA, Shanghai.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 1994 Apr;17(2):90-2, 126.

PMID:7994775
Abstract

Pleural effusions from 28 patients were studied by cytology, chromosome and flow-cytometry. Relative cellular DNA content was measured. An estimate of ploidy as well as cycle distribution has been given. Eighteen patients suffered from malignant effusions while the rest had TB effusions. 83.3% of malignant effusion had aneuploid. The relative cellular DNA content and the cell cycle distribution can provide valuable and decisive information. The study of chromosome also help the diagnosis in addition to cytological results.

摘要

对28例患者的胸腔积液进行了细胞学、染色体和流式细胞术研究。测量了相对细胞DNA含量。给出了倍体以及细胞周期分布的估计值。18例患者患有恶性胸腔积液,其余患者患有结核性胸腔积液。83.3%的恶性胸腔积液为非整倍体。相对细胞DNA含量和细胞周期分布可提供有价值的决定性信息。除细胞学结果外,染色体研究也有助于诊断。

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