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Human centromere mapping using teratoma data.

作者信息

Ott J, Hecht F, Linder D, Lovrien E W, McCaw B K

出版信息

Birth Defects Orig Artic Ser. 1976;12(7):396-8. doi: 10.1159/000130641.

Abstract

Under the assumption that benign ovarian teratomas arise parthenogenetically from a germ cell by suppression of the second meiotic division, the proportion gamma of heteratomas collected from heterozygous hosts is a measure for the distance between the corresponding gene and its centromere. For proportions gamma less than or equal to 0.3, the mapping function x = gamma/2 applies, where x is the map distance in Morgans.

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