Jiménez Cordero A A, Varela de la Torre O I, Cisneros Olivas E
Laboratorio de Patología, Facultad de Medicina, Universidad de Guadalajara.
Ginecol Obstet Mex. 1994 Oct;62:315-8.
We studied 118 patients with primary ovarian cancer at the Civil Hospital of Guadalajara over a ten-years period; to evaluate incidence, risk factors, clinical aspects, pathology and treatment. Twenty per cent of the patients were classified as stage I, 14 cases (11.8%) stage II, 37 (31%) were stage III and 43 (36%), stage IV. First-stage disease was confirmed by laparotomy; average age was fifty years old, commonly found in patients with invasive carcinoma. Seventy-seven patients received postoperative chemotherapy with cisplatin plus adriamycin and ciclophosphamide or vincrystin, and twelve radiotherapy. Thirteen were evaluated by second look laparotomy, 12 of whom were without clinical residual disease; in 6 we found macroscopic residual tumor. Follow-up was done in 89 patients, and there wasn't clinic disease through 12 to 48 months, with 21 months average. The clinicopathologic study showed predominance of serous and cystic surface epithelium tumours. The aspects of the gross anatomy of the malignant tumours are important from the viewpoint of the benign tumours differentiation.
我们在瓜达拉哈拉市民医院对118例原发性卵巢癌患者进行了为期十年的研究，以评估发病率、危险因素、临床症状、病理及治疗情况。20%的患者被归类为I期，14例（11.8%）为II期，37例（31%）为III期，43例（36%）为IV期。一期疾病通过剖腹手术确诊；平均年龄为50岁，常见于浸润性癌患者。77例患者术后接受了顺铂加阿霉素及环磷酰胺或长春新碱的化疗，12例接受了放疗。13例患者接受了二次剖腹探查评估，其中12例无临床残留疾病；6例发现有肉眼可见的残留肿瘤。对89例患者进行了随访，在12至48个月期间无临床疾病，平均为21个月。临床病理研究显示浆液性和囊性表面上皮肿瘤占主导。从良性肿瘤鉴别角度来看，恶性肿瘤的大体解剖特征很重要。
