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Clinical and haemodynamic study of atenolol (Tenormin) in essential hypertension.

作者信息

Jensen H A, Rasmussen K, Mosbaek N

出版信息

Clin Sci Mol Med Suppl. 1976 Dec;3:525s-526s. doi: 10.1042/cs051525s.

DOI:10.1042/cs051525s
PMID:799562
Abstract
  1. The beta1-adrenoreceptor-blocking agent atenolol was studied in the treatment of twelve out-patients with essential hypertension. 2. With a mean dose of 110 mg of atenolol daily (range 75-200 mg/day) we observed a pronounced decrease in blood pressure. 3. Only minimal side effects were seen. 4. Cardiac output decreased from 4-6 to 3-4 l/min during treatment. This decrease did not correlate with the decrease in blood pressure but correlated well with the changes in calculated total peripheral resistance.
摘要

相似文献

1
Clinical and haemodynamic study of atenolol (Tenormin) in essential hypertension.
Clin Sci Mol Med Suppl. 1976 Dec;3:525s-526s. doi: 10.1042/cs051525s.
2
Clinical evaluation of atenolol in hypertension.
Clin Sci Mol Med Suppl. 1976 Dec;3:513s-515s. doi: 10.1042/cs051513s.
3
[Therapeutic effect of the cardioselective beta-blocking agent tenormin and its action on the indices of systemic, intracardiac and regional hemodynamics in patients with hypertension].
Kardiologiia. 1983 Apr;23(4):53-9.
4
Mechanism of hypotensive effect during betaadrenergic blockade in hypertensive patients.高血压患者β肾上腺素能阻滞剂治疗期间的降压机制。
Am Heart J. 1976 May;91(5):634-42. doi: 10.1016/s0002-8703(76)80149-4.
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Haemodynamic long-term effects of a new beta-adrenoceptor blocking drug, atenolol (ICI 66082), in essential hypertension.新型β-肾上腺素能受体阻滞剂阿替洛尔（ICI 66082）对原发性高血压血流动力学的长期影响。
Br J Clin Pharmacol. 1976 Jun;3(3):445-51. doi: 10.1111/j.1365-2125.1976.tb00620.x.
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Mechanism of the haemodynamic interaction between atenolol, a cardioselective beta-adrenoreceptor-blocking agent, and chlorthalidone in hypertensive patients.
Clin Sci (Lond). 1979 Dec;57 Suppl 5:363s-365s. doi: 10.1042/cs057363s.
7
Haemodynamic changes during treatment of arterial hypertension with atenolol (Tenormin).阿替洛尔（氨酰心安）治疗动脉高血压期间的血流动力学变化。
Dan Med Bull. 1980 Jul;27(3):153-5.
8
[Haemodynamic response to antihypertensive treatment with atenolol in patients with hypertension (author's transl].高血压患者使用阿替洛尔降压治疗的血流动力学反应（作者译）
Wien Klin Wochenschr. 1978 Sep 1;90(16):611-6.
9
[Treatment of hypertension with tenormin 100 (atenolol). A general practice study (author's transl)].用天诺敏100（阿替洛尔）治疗高血压。一项全科医疗研究（作者译）
MMW Munch Med Wochenschr. 1980 Dec 5;122(49):1777-80.
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[Clinical use of atenolol (Tenormin) in arterial hypertension].阿替洛尔（氨酰心安）在动脉高血压中的临床应用
Vutr Boles. 1982;21(4):36-41.

引用本文的文献

1
How intrinsic sympathomimetic activity modulates the haemodynamic responses to beta-adrenoceptor antagonists. A clue to the nature of their antihypertensive mechanism.内在拟交感活性如何调节对β-肾上腺素能受体拮抗剂的血流动力学反应。其降压机制本质的一个线索。
Br J Clin Pharmacol. 1982;13(Suppl 2):245S-257S. doi: 10.1111/j.1365-2125.1982.tb01922.x.