Martino F, Ettorre G C, Patella V, Macarini L, Moretti B, Pesce V, Resta L
Institute of Radiology, University of Bari, Italy.
Int J Clin Pharmacol Res. 1993;13 Suppl:35-42.
We propose a modification of the Aisen's technique by which precise reproducible measurements of articular cartilage thickness of the knee is possible. A group of 23 patients with severe osteoarthritis was studied by ultra-sound (US) before knee prosthesis surgery. Evaluation with US was performed by a real-time scanner with a 7.5 MHz linear probe with upper-patellar transverse scans tangent to the upper patellar pole at 90 degrees knee flexion. The cartilage thickness was measured within the weight-bearing area. After surgery, on the corresponding gross pathological specimen, US re-evaluation and histological measurements were made. Results of pre- and post-operative ultrasonography (US) data were compared with histological data and a good correlation between these measurements was found (p(t) > 10%). Preoperative measurements ranged from 2.4 to 0.3 mm. In order to obtain normal reference values of the articular cartilage within the weight-bearing area of the femoral trochlea for comparison, a group of 10 control subjects was also studied with US as above. The US data were then compared with computed tomography (arthro-CT) evaluations. No significant differences in mean values were found between the two imaging techniques (2.2 mm versus 2.3 mm for the lateral condyle and 2.3 versus 2.3 for the medial condyle, respectively). We conclude that ultra-sound measurement of articular cartilage thickness of femoral condyles is a sensitive and reproducible technique which permits early diagnosis and management of knee arthropathy and also quantification of cartilage damage.
我们提出了一种对艾森技术的改进方法,通过该方法可以对膝关节的关节软骨厚度进行精确且可重复的测量。一组23例重度骨关节炎患者在膝关节置换手术前接受了超声(US)检查。使用配备7.5 MHz线性探头的实时扫描仪进行超声评估,在膝关节屈曲90度时,对上髌横向扫描,使其与上髌极相切。在负重区域内测量软骨厚度。手术后,在相应的大体病理标本上进行超声重新评估和组织学测量。将术前和术后超声(US)数据的结果与组织学数据进行比较,发现这些测量之间具有良好的相关性(p(t)>10%)。术前测量值范围为2.4至0.3毫米。为了获得股骨滑车负重区域内关节软骨的正常参考值以作比较,还对一组10名对照受试者进行了上述超声检查。然后将超声数据与计算机断层扫描(关节CT)评估结果进行比较。两种成像技术的平均值之间未发现显著差异(外侧髁分别为2.2毫米对2.3毫米,内侧髁为2.3对2.3)。我们得出结论,超声测量股骨髁关节软骨厚度是一种敏感且可重复的技术,可用于膝关节病的早期诊断和管理,以及软骨损伤的量化。