Martino F, Ettorre G C, Angelelli G, Macarini L, Patella V, Moretti B, D'Amore M, Cantatore F P
Institute of Radiology, University of Bari, Italy.
Clin Rheumatol. 1993 Jun;12(2):178-83. doi: 10.1007/BF02231523.
We studied an echographic technique by which precise reproducible measurements of articular cartilage thickness of the knee is possible. Two groups of individuals were studied: a group of 18 patients with gonarthrosis and a control group of 10 normal individuals. The group of 18 patients with gonarthrosis was studied by ultrasound (US) before knee prosthesis surgery. The cartilage thickness was measured within the weight-bearing area. US re-evaluation and histological measurements were made on the pathological specimen following the operation. Results of pre- and post-operative US data were compared with histological data. A good correlation between these measurements was found [P(t) > 10%]. In order to have comparative reference values of the articular cartilage within the weight-bearing area of the femoral trochlea a group of 10 control subjects was also studied with US as above. We found that the articular cartilage thickness of the femoral trochlea in the weight-bearing area has a mean of 2.2 +/- 0.3 mm for the lateral condyle and 2.3 +/- 0.2 mm for the medial condyle. The intra-observer and inter-observer difference in measurements was evaluated with Student's t-test. Our data demonstrate that US measurements of articular cartilage thickness of femoral condyles is a sensitive and reproducible technique which permits early diagnosis and management of knee arthropathy as well as quantification of cartilage damage.
我们研究了一种超声技术,通过该技术可以对膝关节软骨厚度进行精确且可重复的测量。研究了两组个体:一组为18例膝关节病患者,另一组为10名正常个体作为对照组。对18例膝关节病患者在膝关节假体手术前进行了超声(US)检查。在负重区域测量软骨厚度。术后对病理标本进行超声复查和组织学测量。将术前和术后的超声数据结果与组织学数据进行比较。发现这些测量之间具有良好的相关性[P(t)>10%]。为了获得股骨滑车负重区域内关节软骨的比较参考值,还对一组10名对照受试者进行了上述超声检查。我们发现,负重区域股骨滑车的关节软骨厚度,外侧髁平均为2.2±0.3mm,内侧髁平均为2.3±0.2mm。使用学生t检验评估测量中观察者内和观察者间的差异。我们的数据表明,超声测量股骨髁关节软骨厚度是一种敏感且可重复的技术,可用于膝关节病的早期诊断和管理以及软骨损伤的量化。