Gokal R
Manchester Royal Infirmary, England, UK.
J Postgrad Med. 1993 Oct-Dec;39(4):205-10.
Transplantation is already the optimum treatment for terminal renal failure. Donor organ shortage means that there are large number of patients on dialysis awaiting this treatment. This has in some countries led to unacceptable unscrupulous practices of live non-related graft donation. The outcome of graft and patient after transplantation has improved significantly based on a better understanding of immunopathology, immunosuppression and tissue typing. The future is promising and xenografting may well solve the organ shortage but undoubtedly will raise other issues.
移植已经是终末期肾衰竭的最佳治疗方法。供体器官短缺意味着有大量等待这种治疗的透析患者。在一些国家，这导致了活体非亲属器官捐赠的不道德行为，令人无法接受。基于对免疫病理学、免疫抑制和组织配型的更好理解，移植后移植物和患者的结局有了显著改善。未来充满希望，异种移植很可能解决器官短缺问题，但无疑也会引发其他问题。
