Talbot D
Department of Surgery, Newcastle upon Tyne, UK.
Int Surg. 1999 Oct-Dec;84(4):291-6.
Renal transplantation from its first successful operation in 1954 has become the preferred treatment option of patients with renal failure. The success of this recent development is followed in this article which tabulates surgical, tissue typing and immunosuppressive advancement. This success has produced other problems notably chronic rejection, posttransplant lympho-proliferative disease and donor shortage. The solutions to these problems are discussed, together with a hint of what is to come in the future.
自1954年首次成功进行肾脏移植手术以来,肾脏移植已成为肾衰竭患者首选的治疗方案。本文列出了外科手术、组织分型和免疫抑制方面的进展,跟踪了这一最新进展的成功之处。这一成功也带来了其他问题,尤其是慢性排斥反应、移植后淋巴细胞增殖性疾病和供体短缺。文中讨论了这些问题的解决方案,以及对未来发展的一些暗示。