Kieć-Swierczyńska M
Przychodni Chorób Zawodowych Szpitala Klinicznego, Instytutu Medycyny Pracy, Lodzi.
Med Pr. 1994;45(5):393-8.
Out of 339 persons suffering from occupational dermatitis, the group of 51 patients (15%), allergic to rubber, were eligible for the study. The frequency of allergy to amine compounds and quinoline derivatives (8 chemical compounds), used in rubber mixtures to prevent rubber oxidation, was investigated. The group under study comprised of 20 workers of the metallurgic, 6 of the building and 3 of the rubber industries as well as 15 health service workers, 2 farmers and 5 drivers. Allergy to amine compounds was found in 30 persons (58.8%) and to quinoline derivatives in 5 persons (9.8%). N-isopropyl-N-phenyl-4-phenylenodiamine proved to be most allergenic (52.9% of allergic persons), then N-cyclohexyl-N-phenyl-4-phenylenodiamine (31.4%) and N,N-diphenyl-4-phenylenodiamine (23.5%). Allergy to amine antioxidants was two times higher among workers of the metallurgic and building industries as well as among farmers and drivers than in health service workers, and it was induced by contact with technical rubber.
在339名职业性皮炎患者中，51名对橡胶过敏的患者（15%）符合研究条件。研究了橡胶混合物中用于防止橡胶氧化的胺类化合物和喹啉衍生物（8种化合物）的过敏频率。研究组包括20名冶金行业工人、6名建筑行业工人、3名橡胶行业工人以及15名卫生服务人员、2名农民和5名司机。30人（58.8%）对胺类化合物过敏，5人（9.8%）对喹啉衍生物过敏。结果表明，N-异丙基-N-苯基-4-苯二胺致敏性最强（占过敏者的52.9%），其次是N-环己基-N-苯基-4-苯二胺（31.4%）和N,N-二苯基-4-苯二胺（23.5%）。冶金和建筑行业的工人以及农民和司机对胺类抗氧化剂的过敏率是卫生服务人员的两倍，且这种过敏是由接触工业橡胶引起的。
