Go R T, MacIntyre W J, Saha G B, Cook S A, Neumann D R, Chen E Q, Underwood D A, Kaczur T
Department of Nuclear Medicine, Cleveland Clinic Foundation, OH 44195-5074.
Radiology. 1995 Jan;194(1):151-5. doi: 10.1148/radiology.194.1.7997543.
To determine whether quantitation of the relative severity of decreased perfusion in irreversible defects on myocardial perfusion images enables differentiation of viable hibernating myocardium from scar.
In 145 patients with previous myocardial infarction, 1,252 regions with irreversible defects proved by means of rubidium-82 rest-stress imaging were analyzed for relative severity (percentage decrease in perfusion). Myocardial tissue viability was determined by means of positron emission tomography with fluorine-18 fluorodeoxyglucose (FDG).
The relative decreases in Rb-82 uptake in the 1,252 regions were categorized into nine levels of severity (30% to > or = 70%) in 381 regions of hibernating myocardium and 871 regions of scar. The values of relative decreased perfusion in the irreversible defects alone did not enable differentiation of hibernating myocardium and scar (P = .61).
The results show no relationship between the relative severity of irreversible perfusion defects and the ability to distinguish between hibernating myocardium and scar.
确定心肌灌注图像中不可逆缺损处灌注降低的相对严重程度的定量分析能否区分存活的冬眠心肌与瘢痕组织。
在145例既往有心肌梗死的患者中，对通过铷-82静息-负荷成像证实存在不可逆缺损的1252个区域进行相对严重程度（灌注降低百分比）分析。采用氟-18氟脱氧葡萄糖（FDG）正电子发射断层扫描确定心肌组织活力。
1252个区域铷-82摄取的相对降低被分为9个严重程度等级（30%至≥70%），其中381个区域为冬眠心肌，871个区域为瘢痕组织。仅根据不可逆缺损处灌注相对降低的值无法区分冬眠心肌和瘢痕组织（P = 0.61）。
结果表明不可逆灌注缺损的相对严重程度与区分冬眠心肌和瘢痕组织的能力之间无相关性。
