Niclot P, Pollin B, N'Guyen J, Cesaro P, Degos J D
Collège de France (Paris), Laboratoire de Neurophysiologie.
Rev Neurol (Paris). 1993;149(12):755-63.
Thalamotomy in the ventrolateral thalamic nucleus is a common treatment of severe parkinsonian or essential tremor. Although results are often satisfactory, complications may occur and alter the success of the operation. High frequency stimulation of the target before thalamotomy leads to transitory abolition of the tremor. Therefore, a chronic stimulation device was developed and its use produced results similar to those of thalamotomy for parkinsonian tremor. Unwanted side-effect can be reduced by changing the parameters of the stimulation. Improvements in multiple sclerosis and post-traumatic tremors may be expected. We present a review of the indications and results of both technics.
丘脑腹外侧核毁损术是治疗重度帕金森病或特发性震颤的常用方法。尽管治疗结果通常令人满意,但仍可能出现并发症并影响手术的成功率。在丘脑毁损术前对靶点进行高频刺激可导致震颤暂时消失。因此,研发了一种慢性刺激装置,其应用产生的结果与丘脑毁损术治疗帕金森震颤的结果相似。通过改变刺激参数可减少不良副作用。预计对多发性硬化症和创伤后震颤也有改善作用。我们对这两种技术的适应症和结果进行了综述。