Sandbaek G, Brekke M
Røntgenavdelingen, Aker sykehus, Oslo.
Tidsskr Nor Laegeforen. 1994 Nov 30;114(29):3446-9.
The treatment of acute and subacute arterial occlusions poses a difficult clinical problem. Local intra-arterial thrombolysis can be a useful therapeutic alternative. The most commonly used thrombolytic agents are considered. In the treatment of artery or graft occlusions in the lower extremities, the best results are achieved if the occlusion is proximal, short and recent. The authors discuss selection of patients, technique and results. In the coronary arteries the time factor is crucial. Local intracoronary thrombolysis is used most often as an adjunctive treatment to balloon angioplasty and stent implantation. Good run-off and correction of the flow-limiting lesion greatly improves the outcome in both the peripheral and coronary arteries.
急性和亚急性动脉闭塞的治疗是一个棘手的临床问题。局部动脉内溶栓可能是一种有效的治疗选择。文中考虑了最常用的溶栓药物。在治疗下肢动脉或移植物闭塞时，如果闭塞部位在近端、长度较短且发生时间较近，则能取得最佳效果。作者讨论了患者的选择、技术及结果。在冠状动脉中，时间因素至关重要。局部冠状动脉内溶栓最常作为球囊血管成形术和支架植入的辅助治疗。良好的血流灌注以及对限流性病变的矫正，能显著改善外周动脉和冠状动脉疾病的治疗效果。
