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[胰岛素依赖型糖尿病女性的不孕与妊娠结局。一项流行病学研究]

[Infertility and pregnancy outcome in women with insulin-dependent diabetes. An epidemiological study].

作者信息

Pedersen K K, Hagen C, Sandø-Pedersen S H, Eshøj O

机构信息

Odense Universitetshospital, medicinsk endokrinologisk afdeling M.

出版信息

Ugeskr Laeger. 1994 Oct 17;156(42):6196-200.

PMID:7998356
Abstract

A questionnaire survey comprising an unselected group of 18-49-year old women with insulin-dependent diabetes mellitus and an age comparable control group was performed. Two hundred and forty-five (94%) of the diabetic women and 253 (88%) of the controls answered questions concerning fertility, pregnancy planning and pregnancy outcome. There was no difference in the cumulative rate of pregnancies in the two groups. The prevalence of involuntary infertility among the diabetic women was 17% and similar to that of controls. Compared to controls, diabetic women had significantly fewer pregnancies (mean 1.4 versus 1.7) and fewer births per pregnancy (70% versus 77%), and significantly more diabetic women were nulliparous (48% versus 38%). Only about half of all pregnancies were planned. In general the diabetic women reported that their diabetes had a negative influence on their attitude towards having children.

摘要

对一组未经挑选的18至49岁胰岛素依赖型糖尿病女性患者以及一个年龄匹配的对照组进行了问卷调查。245名(94%)糖尿病女性和253名(88%)对照组女性回答了有关生育、妊娠计划和妊娠结局的问题。两组的累积妊娠率没有差异。糖尿病女性中意外不孕症的患病率为17%,与对照组相似。与对照组相比,糖尿病女性的妊娠次数显著较少(平均1.4次对1.7次),每次妊娠的分娩次数也较少(70%对77%),并且未生育的糖尿病女性明显更多(48%对38%)。所有妊娠中只有约一半是计划内的。总体而言,糖尿病女性报告称她们的糖尿病对其生育态度有负面影响。

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Ugeskr Laeger. 1994 Oct 17;156(42):6196-200.
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