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[诊断性抗磷脂抗体及其临床意义]

[Diagnostic antiphospholipid antibodies and their clinical significance].

作者信息

Palester-Chlebowczyk M

机构信息

Kliniki Chirurgii Naczyń i Transplantologii Akademii Medycznej, Warszawie.

出版信息

Acta Haematol Pol. 1994;25(2 Suppl 2):67-74.

PMID:7998477
Abstract

Lupus anticoagulant and anticardiolipin antibodies belong to a heterogeneous family of antiphospholipid antibodies, directed probably against complexes composed of protein and negatively charged phospholipids. The antiphospholipid syndrome consists in the association of antiphospholipid antibodies and both venous and arterial occlusive events. The mechanism by which the antiphospholipid antibodies could induce thrombosis remains unclear.

摘要

狼疮抗凝物和抗心磷脂抗体属于抗磷脂抗体的异质性家族,可能针对由蛋白质和带负电荷的磷脂组成的复合物。抗磷脂综合征包括抗磷脂抗体与静脉和动脉闭塞事件的关联。抗磷脂抗体诱导血栓形成的机制尚不清楚。

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