Marini R P, Jackson L R, Esteves M I, Andrutis K A, Goslant C M, Fox J G
Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge 02139.
Am J Vet Res. 1994 Oct;55(10):1479-83.
Effects of isoflurane on the CBC in ferrets were studied. There was rapid decrease in all hematologic variables after induction of anesthesia. Percentage reductions in indices of the erythron (hematocrit, RBC count, hemoglobin concentration) exceeded those of plasma protein concentration and WBC count at the first postinduction time point. There was little additional decrease in these variables for the duration of anesthesia. The values had partially recovered to preanesthetic baseline at 45 minutes after anesthesia. Although these alterations appear to be well tolerated in healthy ferrets, care should be exercised when subjecting anemic, geriatric, or debilitated ferrets to isoflurane-induced anesthesia.
研究了异氟烷对雪貂全血细胞计数（CBC）的影响。麻醉诱导后，所有血液学指标迅速下降。诱导后第一个时间点，红细胞系指标（血细胞比容、红细胞计数、血红蛋白浓度）的降低百分比超过血浆蛋白浓度和白细胞计数。在麻醉期间，这些指标几乎没有进一步下降。麻醉后45分钟，这些指标部分恢复到麻醉前基线水平。虽然这些改变在健康雪貂中似乎耐受性良好，但在对贫血、老年或体弱的雪貂进行异氟烷诱导麻醉时应谨慎操作。
