Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado.
Laboratory Animal Resources, Colorado State University, Fort Collins, Colorado.
J Am Assoc Lab Anim Sci. 2020 May 1;59(3):275-281. doi: 10.30802/AALAS-JAALAS-19-000056. Epub 2020 Mar 12.
Jamaican fruit bats () are used as an animal model for several viruses, including Middle East respiratory syndrome virus, dengue virus, Zika virus, and Tacaribe virus. However, despite ongoing studies regarding these pathogens, little is known regarding the bats' normal physiology. In this study, phlebotomy of the propetagial (cephalic) vein was performed to establish baseline hematologic parameters in an apparently healthy, captive population of Jamaican fruit bats. Furthermore, we compared results from physically restrained and isoflurane-anesthetized bats. Our findings indicate significant increases in WBC count, lymphocytes, and monocytes in the anesthetized bats. However, RBC and platelet parameters were not different between the 2 groups. This information on the normal hematologic parameters of Jamaican fruit bats, adds to our overall understanding of the normal physiology of this species, and expands our knowledge on bat species in general.
牙买加果蝠（）被用作几种病毒的动物模型，包括中东呼吸综合征病毒、登革热病毒、寨卡病毒和塔卡里伯病毒。然而，尽管对这些病原体的研究一直在进行，但对于蝙蝠的正常生理机能却知之甚少。在这项研究中，对 propetagial（头侧）静脉进行了采血，以建立一个明显健康的、圈养的牙买加果蝠种群的基础血液学参数。此外，我们比较了物理约束和异氟烷麻醉的蝙蝠的结果。我们的发现表明，在麻醉的蝙蝠中，白细胞计数、淋巴细胞和单核细胞显著增加。然而，红细胞和血小板参数在两组之间没有差异。关于牙买加果蝠正常血液学参数的这些信息，增加了我们对该物种正常生理学的整体理解，并扩展了我们对一般蝙蝠物种的知识。
