St Clair Morgan O
Department of Medicine, University of the West Indies, Jamaica, West Indies.
Mol Neurobiol. 1994 Apr-Jun;8(2-3):149-53. doi: 10.1007/BF02780666.
This article summarizes the present state of knowledge of TSP/HAM as it is seen in Jamaica. It reviews the historical and clinical aspects of the disease, and shows how the discovery of HTLV-I has generated research in several countries and contributed to a better understanding of the disease. It highlights the need for continued collaboration between basic scientists and clinical neurologists in order that the dilemmas relating to therapy and pathogenicity may be successfully addressed.
本文总结了在牙买加所观察到的热带痉挛性轻截瘫/人类嗜T淋巴细胞病毒I型相关脊髓病(TSP/HAM)的现有知识状况。它回顾了该疾病的历史和临床方面,并展示了人类嗜T淋巴细胞病毒I型(HTLV-I)的发现如何在多个国家引发了研究,并有助于更好地理解该疾病。它强调了基础科学家和临床神经学家持续合作的必要性,以便成功解决与治疗和致病性相关的难题。