Barasch E, Wilansky S
Department of Adult Cardiology, Texas Heart Institute, Houston.
Tex Heart Inst J. 1994;21(3):202-10.
Stress echocardiography has been developed in recent years as an effective noninvasive test for the detection and assessment of coronary artery disease. This method combines exercise with 2-dimensional echocardiography, which can assess regional and global left ventricular function during stress. Dobutamine infusion, a pharmacologic means of producing cardiovascular stress, appears to be an excellent alternative to exercise in echocardiographic studies. Currently, it is reserved for patients who cannot exercise at a meaningful level because of advanced age, physical deconditioning, or other factors. This review evaluates the current clinical application of dobutamine stress echocardiography and compares its efficacy with that of exercise echocardiography and nuclear perfusion imaging.
近年来,负荷超声心动图已发展成为一种用于检测和评估冠状动脉疾病的有效的非侵入性检查方法。该方法将运动与二维超声心动图相结合,能够在负荷状态下评估局部和整体左心室功能。多巴酚丁胺输注作为一种产生心血管负荷的药理学手段,在超声心动图研究中似乎是运动的一种极佳替代方法。目前,它适用于因高龄、身体状况不佳或其他因素而无法进行有效运动的患者。本综述评估了多巴酚丁胺负荷超声心动图的当前临床应用,并将其疗效与运动超声心动图和核灌注成像的疗效进行比较。