Patsalos P N
Pharmacology and Therapeutics Unit, Chalfont Centre for Epilepsy, Bucks, UK.
Seizure. 1994 Sep;3(3):163-70. doi: 10.1016/s1059-1311(05)80184-0.
With the introduction of three new anti-epileptic drugs (AEDs) in the UK during the past 4 years as adjunctive add-on therapy, the possibility of AED pharmacokinetic interactions has become a relevant consideration. This review highlights the current status of AED interactions with particular emphasis on those interactions that are likely to be frequently experienced or whose outcome is potentially clinically significant.
在过去4年里，英国引入了3种新型抗癫痫药物（AEDs）作为辅助附加疗法，AEDs药代动力学相互作用的可能性已成为一个相关的考虑因素。本综述重点介绍了AEDs相互作用的现状，特别强调了那些可能经常出现或其结果可能具有临床重要意义的相互作用。
