Wellings R M, Davies A M, Pynsent P B, Cassar-Pullicino V N
Department of Radiology, Royal Orthopaedic Hospital, Birmingham, UK.
Br J Radiol. 1994 Oct;67(802):941-4. doi: 10.1259/0007-1285-67-802-941.
The physico-chemical properties of the iso-osmolar dimeric contrast medium iotrolan offers potential advantages in computed tomographic arthrography (CTA). A trial was undertaken comparing iotrolan with iohexol to assess if these theoretical benefits produced an increase in the measured densities in a series of shoulder CTAs. The results showed that iotrolan did produce clinically useful increases in density when compared to a monomeric non-ionic contrast medium. The addition of adrenaline to the monomeric contrast medium produced a significant improvement in the computed tomography density which surpassed that offered by the dimeric contrast medium alone.
等渗二聚体造影剂碘曲仑的物理化学性质在计算机断层关节造影（CTA）中具有潜在优势。进行了一项将碘曲仑与碘海醇进行比较的试验，以评估这些理论上的优势是否会使一系列肩部CTA的测量密度增加。结果表明，与单体非离子型造影剂相比，碘曲仑确实在临床上使密度有了有用的增加。向单体造影剂中添加肾上腺素显著改善了计算机断层扫描密度，超过了单独使用二聚体造影剂所提供的密度。
