van Bree H, Van Rijssen B, Tshamala M, Maenhout T
Department of Radiology, State University of Ghent, Belgium.
Am J Vet Res. 1992 Sep;53(9):1622-6.
Arthrographic quality and synovial inflammatory response were examined to compare the use of iopromide with that of iotrolan for arthrography of the scapulohumeral joint in 6 dogs. Radiographs obtained 1 and 3 minutes after injection of either nonionic compound were of similar quality, but radiographs obtained 5 minutes after injection of iotrolan were significantly (P less than 0.05) better than those obtained after injection of iopromide. Results of analysis of synovial fluid samples obtained at 1, 3, 7, and 14 days after injection of contrast media were not significantly different between the 2 groups. Histologic examination of synovium and articular cartilage 2 weeks after injection of iopromide or iotrolan revealed minimal inflammatory response for both contrast agents. Injection of iopromide and iotrolan into the scapulohumeral joints of dogs had less effect on synovial fluid than that reported after injection of ionic compounds.
为比较碘普罗胺和碘曲仑在6只犬肩胛肱关节造影中的应用，对造影质量和滑膜炎症反应进行了检查。注射两种非离子化合物后1分钟和3分钟获得的X线片质量相似，但注射碘曲仑后5分钟获得的X线片明显（P<0.05）优于注射碘普罗胺后获得的X线片。注射造影剂后1天、3天、7天和14天采集的滑液样本分析结果在两组之间无显著差异。注射碘普罗胺或碘曲仑2周后对滑膜和关节软骨进行组织学检查，结果显示两种造影剂的炎症反应均最小。向犬的肩胛肱关节注射碘普罗胺和碘曲仑对滑液的影响小于注射离子化合物后报告的影响。
