Gilliland F D, Key C R
Department of Medicine, New Mexico Tumor Registry, University of New Mexico School of Medicine, Albuquerque 87131.
Cancer. 1995 Jan 1;75(1 Suppl):295-315. doi: 10.1002/1097-0142(19950101)75:1+<295::aid-cncr2820751313>3.0.co;2-u.
The estimated 165,000 cancers of the male genital system that will occur in the United States during 1993 represent one fourth of the expected 600,000 newly diagnosed cancers in American males for the year.
Data were collected by the Surveillance, Epidemiology, and End Results (SEER) program. This paper examines histologic data collected by the SEER program from 1973-1987 and focuses on incidence, stage at diagnosis, and survival for the dominant histologic types of cancer that occur in the four major topographic divisions of the male genital system: prostate gland, testis, penis, and scrotum. Some less common histologic types within each organ are also discussed.
The incidence of male genital cancer has increased rapidly over the period of study. Cancers of the prostate, most of which are adenocarcinomas, represent more than 92% of all male genital cancers. Among adolescents and young men, germ cell cancers of the testis predominate, but decline rapidly in occurrence after 40 years of age. Blacks had higher incidence rates for prostate cancer than whites; however, the situation was reversed for testicular cancer. Survival increased dramatically for testicular cancer. Cancers of the penis and scrotum of any histologic type are uncommon in the United States.
The increased incidence of prostate adenocarcinomas and testis germ cell tumors indicates the need for further etiologic studies as a basis for prevention efforts.
1993年在美国预计发生的16.5万例男性生殖系统癌症占当年美国男性预计60万例新诊断癌症的四分之一。
数据由监测、流行病学和最终结果(SEER)项目收集。本文研究了SEER项目在1973 - 1987年收集的组织学数据,重点关注男性生殖系统四个主要解剖部位(前列腺、睾丸、阴茎和阴囊)中主要组织学类型癌症的发病率、诊断时的分期和生存率。每个器官内一些不太常见的组织学类型也进行了讨论。
在研究期间,男性生殖系统癌症的发病率迅速上升。前列腺癌,其中大多数是腺癌,占所有男性生殖系统癌症的92%以上。在青少年和年轻男性中,睾丸生殖细胞癌占主导,但40岁以后发病率迅速下降。黑人前列腺癌的发病率高于白人;然而,睾丸癌的情况则相反。睾丸癌的生存率显著提高。在美国,任何组织学类型的阴茎癌和阴囊癌都不常见。
前列腺腺癌和睾丸生殖细胞肿瘤发病率的上升表明需要进一步开展病因学研究,作为预防工作的基础。