Baron J, Warenik-Szymankiewicz A, Miedzianowski J, Baron J J
Kliniki Endokrynologii Gin, Instytutu Ginekologii i Połoznietwa w Poznaniu.
Ginekol Pol. 1994 Mar;65(3):115-20.
In the last 35 years we noticed 91 cases of Turner's syndrome. To the obligatory symptoms of the syndrome belong primary amenorrhoea, sexual infantilism, elevated values only of FSH and very reduced levels of estrogens, chromosomal aberrations in karyotype, most often 45, X and presence of streak gonads. The facultative symptoms of the syndrome belong short stature (94.5% of patients), presence of congenital defects (short webbed neck in 44.4%) and sterility (98.9%). Therapy above 15 years excepting to cause the menstrual cycles have to development the second sexual symptoms by giving enough large doses of oestrogens and gestagens. The best effects we obtain nearly in 100% in the development of breasts, in slowly growth of sexual hair and in the growth of the stature which does not cross the height of 150 cm and only in six patients attained in average 152.5 cm.
在过去35年里，我们发现了91例特纳综合征病例。该综合征的必备症状包括原发性闭经、性幼稚、仅促卵泡生成素值升高而雌激素水平极低、核型染色体畸变，最常见的是45,X以及条索状性腺的存在。该综合征的兼发症状包括身材矮小（94.5%的患者）、存在先天性缺陷（44.4%有短蹼颈）和不育（98.9%）。15岁以上的治疗除了要促使月经周期出现外，还必须通过给予足够大剂量的雌激素和孕激素来促使第二性征发育。我们在乳房发育、性毛缓慢生长以及身高增长方面几乎100%取得了最佳效果，身高不超过150厘米，只有6例患者平均达到了152.5厘米。
