O'Connell D M, Fagan W A, Skinner S M, Pulitzer D R, Devillez R L
Department of Dermatology, University of Texas Health Science Center, San Antonio 78284-7876.
Int J Dermatol. 1994 Sep;33(9):628-31. doi: 10.1111/j.1365-4362.1994.tb02920.x.
Chronic myelomonocytic leukemia has been associated with various nonspecific cutaneous manifestations. Rarely has the leukemia been reported to directly affect the skin.
This case documents the progression of a patient who ultimately developed chronic myelomonocytic leukemia, by clinical examination, hematologic parameters, dermatopathology, and bone marrow pathology.
The skin showed nonspecific cutaneous involvement, progressing to specific leukemic lesions parallel with increasing systemic and hematologic involvement.
Chronic myelomonocytic leukemia can manifest with lesions of leukemia cutis. The possibility of nonspecific cutaneous involvement in the preleukemic phase exists.
慢性粒单核细胞白血病与多种非特异性皮肤表现相关。很少有报道称白血病会直接累及皮肤。
本病例通过临床检查、血液学参数、皮肤病理学和骨髓病理学记录了一名最终发展为慢性粒单核细胞白血病患者的病情进展。
皮肤表现为非特异性皮肤受累，随着全身和血液学受累程度的增加，进展为特异性白血病皮损。
慢性粒单核细胞白血病可表现为皮肤白血病皮损。白血病前期存在非特异性皮肤受累的可能性。
