Sperling L C, Skelton H G, Smith K J, Sau P, Friedman K
Dermatology Service, Walter Reed Army Medical Center, Washington, DC.
Arch Dermatol. 1994 Jun;130(6):763-9.
Follicular degeneration syndrome (FDS, formerly called hot comb alopecia) has only been described in black women. The clinical and histologic features of eight black men with a scarring alopecia resembling FDS were studied.
All eight men had evidence of scarring alopecia, which was most prominent on the crown of the scalp. None of the men were using chemical or physical modalities to straighten or style the hair. Overall, this group of men had more evidence of active inflammation than did the previously described women with FDS. The histologic features in the men were identical to those found in women with FDS. The presence of premature desquamation of the inner root sheath and migration of the hair shaft through the outer root sheath serve as histologic markers of FDS and separate it histologically from other forms of scarring alopecia.
Follicular degeneration syndrome is a common form of scarring alopecia in black men, just as it is in black women. In men, there is no association between chemical or mechanical hair styling techniques (eg, the "hot comb") and onset, progression, or severity of disease. The histologic features of FDS in men are identical to those in women.
毛囊退化综合征（FDS，以前称为热梳脱发症）仅在黑人女性中被描述过。对八名患有类似FDS的瘢痕性脱发的黑人男性的临床和组织学特征进行了研究。
所有八名男性均有瘢痕性脱发的证据，在头顶最为明显。这些男性均未使用化学或物理方法来拉直或造型头发。总体而言，与先前描述的患有FDS的女性相比，这组男性有更多的活动性炎症证据。男性的组织学特征与患有FDS的女性相同。内根鞘过早脱屑以及毛干穿过外根鞘迁移是FDS的组织学标志，并在组织学上将其与其他形式的瘢痕性脱发区分开来。
毛囊退化综合征是黑人男性中常见的瘢痕性脱发形式，就像在黑人女性中一样。在男性中，化学或机械头发造型技术（例如“热梳”）与疾病的发作、进展或严重程度之间没有关联。男性FDS的组织学特征与女性相同。
