Davis Erica C, Reid Sophia D, Callender Valerie D, Sperling Leonard C
J Clin Aesthet Dermatol. 2012 Jun;5(6):37-40.
Central centrifugal cicatricial alopecia is a scarring alopecia that is predominantly seen in African American women, but occurs less frequently in men. The authors present three cases of African American men with biopsy-proven central centrifugal cicatricial alopecia and detail the clinical presentation, histological findings, and treatment regimens. Central centrifugal cicatricial alopecia should be considered in the differential diagnosis when evaluating male patients with vertex hair loss accompanied by scalp symptoms. Physicians should maintain a high index of suspicion in African American men with the appropriate clinical picture and confirm the diagnosis by scalp biopsy. Prompt and appropriate treatment can help halt or slow disease progression.
中心离心性瘢痕性秃发是一种瘢痕性秃发,主要见于非裔美国女性,但在男性中较少见。作者报告了3例经活检证实为中心离心性瘢痕性秃发的非裔美国男性病例,并详细阐述了临床表现、组织学发现及治疗方案。在评估有头顶脱发并伴有头皮症状的男性患者时,应将中心离心性瘢痕性秃发纳入鉴别诊断。对于有相应临床表现的非裔美国男性,医生应保持高度怀疑,并通过头皮活检确诊。及时且恰当的治疗有助于阻止或减缓疾病进展。