Han C M, Grimmond T R
P N G Med J. 1976 Dec;19(4):236-42.
The response of Plasmodium falciparum infections to a standard weight related dose of chloroquine using the W.H.O. Extended Field Test was investigated in the Maprik and Popondetta areas of Papus New Guinea. Fourteen cases of P. falciparum in Maprik and 12 cases at Popondetta were followed daily for seven days and weekly for a further three weeks after receiving 25 mg/kg of chloroquine over three days. All subjects responded well, the parasitaemias cleared in all cases by the fourth day after initiation of treatment and no recrudescences occurred in any subject in the month following therapy. No indication of chloroquine resistance was found in these two areas.
在巴布亚新几内亚的马普里克和波波佩塔地区，采用世界卫生组织扩大现场试验，研究了恶性疟原虫感染对标准体重相关剂量氯喹的反应。在马普里克的14例恶性疟原虫病例和波波佩塔的12例病例中，在三天内接受25毫克/千克氯喹后，每天观察七天，随后三周每周观察一次。所有受试者反应良好，治疗开始后第四天所有病例的疟原虫血症均清除，治疗后一个月内任何受试者均未出现复发。在这两个地区未发现氯喹耐药的迹象。
