Leoni A, Fadda M, Nieddu A M, Pittau M, Sanna E, Pirino S, Contini A
Istituto di Patologia Generale e Anatomia Patologica Veterinaria, Università degli Studi di Sassari.
Boll Soc Ital Biol Sper. 1993 Dec;69(12):775-82.
A severe exudative-crustous and proliferous dermatitis in a 2 year old sheep caused by Dermatophilus congolensis (observed for the first time in Italy), is reported. The disease was reproduced experimentally in sheep, goats, rabbits and guinea pigs, whose skin was treated in different ways before infection. E.L.I.S.A. and Immunoblotting tests carried out in experimentally infected sheep, showed the antigenic complexity of the pathogen and the existence of cross-immunity to the protein components. Intradermoreaction tests were carried out in all animals. The development of a positive reaction only in rabbits and guinea pigs, confirmed that these animals have a cellular immunity against Dermatophilus congolensis.
报道了一例由刚果嗜皮菌引起的两岁绵羊严重渗出性结痂和增生性皮炎（首次在意大利观察到）。该疾病在绵羊、山羊、兔子和豚鼠身上进行了实验性再现，在感染前对它们的皮肤进行了不同方式的处理。对实验感染绵羊进行的酶联免疫吸附测定（ELISA）和免疫印迹试验显示了病原体的抗原复杂性以及对蛋白质成分存在交叉免疫。对所有动物都进行了皮内反应试验。仅在兔子和豚鼠身上出现阳性反应，证实这些动物对刚果嗜皮菌具有细胞免疫。
