Knopp J, Zaliberová Y, Jurcovicová J, Torda T, Brtko J
Intitute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava.
Endocr Regul. 1993 Mar;27(1):26-8.
The specific binding of prolactin (PRL) in rat liver nuclei have been examined. Following cross-linking with the use of 125I-rat prolactin and autoradiography the evidence is presented for the specific binding of PRL to a nuclear protein with low Mr of about 7000. This study shows that the PRL binder in rat liver nuclei is a small protein and probably differs from molecular form of the rat liver membrane prolactin receptor.
已对催乳素（PRL）在大鼠肝细胞核中的特异性结合进行了研究。在用¹²⁵I - 大鼠催乳素进行交联并放射自显影后，有证据表明PRL与一种低分子量约为7000的核蛋白发生特异性结合。这项研究表明，大鼠肝细胞核中的PRL结合蛋白是一种小蛋白，可能与大鼠肝细胞膜催乳素受体的分子形式不同。
