• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

淋巴细胞受体。I. 携带免疫球蛋白、具有抗原结合能力及抗体分泌能力的细胞上的IgG Fc及补体（C3b）受体

Lymphocyte receptors. I. Receptors for Fc of IgG and complement (C3b) on immunoglobulin-bearing, antigen-binding and antibody-secreting cells.

作者信息

McConnell I, Hurd C M

出版信息

Immunology. 1976 Jun;30(6):825-33.

PMID:800392
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1445064/
Abstract

Immunoglobulin (Ig) bearing, antigen-binding and antibody-secreting cells were investigated for the presence of membrane receptors for the Fc part of IgG and for C3b on their surface. Fc and C3b receptors were detected on the surface of most Ig-bearing and of most antigen-binding cells. Fc receptors were also detected on IgM antibody-secreting cells but not on IgG-secreting cells. C3b receptors were not detected on any antibody-secreting cells. These receptors are either lost from the B cell surface as they differentiate into antibody-secreting cells or are blocked in vivo by immune complexes or C3b.

摘要

对携带免疫球蛋白（Ig）、具有抗原结合能力和抗体分泌功能的细胞进行研究，以检测其表面是否存在针对IgG的Fc部分和C3b的膜受体。在大多数携带Ig的细胞和大多数抗原结合细胞表面检测到了Fc和C3b受体。在分泌IgM抗体的细胞表面也检测到了Fc受体，但在分泌IgG的细胞表面未检测到。在任何抗体分泌细胞表面均未检测到C3b受体。这些受体要么在B细胞分化为抗体分泌细胞时从其表面丢失，要么在体内被免疫复合物或C3b阻断。

相似文献

1
Lymphocyte receptors. I. Receptors for Fc of IgG and complement (C3b) on immunoglobulin-bearing, antigen-binding and antibody-secreting cells.淋巴细胞受体。I. 携带免疫球蛋白、具有抗原结合能力及抗体分泌能力的细胞上的IgG Fc及补体（C3b）受体
Immunology. 1976 Jun;30(6):825-33.
2
Human peripheral lymphocytes bearing surface immunoglobulin do not have readily detectable Fc receptors.带有表面免疫球蛋白的人外周淋巴细胞没有易于检测到的Fc受体。
Clin Exp Immunol. 1978 Aug;33(2):332-9.
3
Ontogeny of the antibody-forming cell line in mice. IV. Appearance of cells bearing Fc receptors, complement receptors, and surface immunoglobulin.小鼠抗体形成细胞系的个体发生。IV. 带有Fc受体、补体受体和表面免疫球蛋白的细胞的出现。
J Immunol. 1977 Feb;118(2):612-7.
4
Surface markers of complement receptor lymphocytes.补体受体淋巴细胞的表面标志物。
J Clin Invest. 1978 Nov;62(5):1086-92. doi: 10.1172/JCI109214.
5
Binding of soluble immune complexes to human lymphoblastoid cells. I. Characterization of receptors for IgG Fc and complement and description of the binding mechanism.可溶性免疫复合物与人淋巴母细胞的结合。I. IgG Fc和补体受体的特性及结合机制的描述。
J Exp Med. 1974 Oct 1;140(4):877-94. doi: 10.1084/jem.140.4.877.
6
Interrelationships of surface immunoglobulin and Fc receptors on mouse B lymphocytes.小鼠B淋巴细胞表面免疫球蛋白与Fc受体的相互关系。
J Immunol. 1975 Dec;115(6):1665-71.
7
The specificity of the Fc receptor on murine lymphocytes for immunoglobulins of the IgG and IgM classes.小鼠淋巴细胞上Fc受体对IgG和IgM类免疫球蛋白的特异性。
Immunology. 1976 Jun;30(6):851-8.
8
C3 binds with similar efficiency to Fab and Fc regions of IgG immune aggregates.C3以相似的效率与IgG免疫聚集体的Fab和Fc区域结合。
Eur J Immunol. 1994 Mar;24(3):599-604. doi: 10.1002/eji.1830240316.
9
Interactions between lymphocyte membrane molecules. II. Characterization of an interaction between B lymphocyte surface IgD and Fc IgG receptors that differs from the surface IgM-Fc IgG receptor interaction.淋巴细胞膜分子间的相互作用。II. B淋巴细胞表面IgD与Fc IgG受体间相互作用的特性，该相互作用不同于表面IgM-Fc IgG受体间的相互作用。
J Immunol. 1982 Mar;128(3):1271-7.
10
Fc receptor heterogeneity: immunofluorescent studies of B, T, and "third population" lymphocytes in human blood with rabbit IgG b4/anti-b4 complexes.Fc受体异质性：用人血中的B淋巴细胞、T淋巴细胞和“第三类群体”淋巴细胞与兔IgG b4/抗b4复合物进行免疫荧光研究。
J Immunol. 1977 Nov;119(5):1778-84.

引用本文的文献

1
Unraveling the enigma of long COVID: novel aspects in pathogenesis, diagnosis, and treatment protocols.揭开长新冠之谜：发病机制、诊断和治疗方案的新方面。
Inflammopharmacology. 2024 Aug;32(4):2075-2090. doi: 10.1007/s10787-024-01483-2. Epub 2024 May 21.
2
IgG and complement receptors on purified mouse eosinophils and neutrophils.纯化小鼠嗜酸性粒细胞和中性粒细胞上的IgG及补体受体
Immunology. 1981 Aug;43(4):779-86.
3
[Intercellular contacts in chronic rhinosinusitis and their possible significance. A light and electron microscopic investigation (author's transl)].[慢性鼻窦炎中的细胞间接触及其可能的意义。光镜和电镜研究（作者译）]
Arch Otorhinolaryngol. 1977 May 31;215(3-4):265-82. doi: 10.1007/BF00463064.
4
Terminal B cell development as seen in different human myelomas and related disorders.在不同的人类骨髓瘤及相关疾病中所见的终末B细胞发育。
Clin Exp Immunol. 1979 Feb;35(2):180-9.
5
The response to lipopolysaccharide of mouse spleen lymphocytes fractionated on the basis of surface immunoglobulin and complement receptor using fluorescence-activated cell sorting and rosetting techniques.使用荧光激活细胞分选和花环形成技术，对基于表面免疫球蛋白和补体受体进行分离的小鼠脾脏淋巴细胞的脂多糖反应。
Immunology. 1979 Apr;36(4):865-73.
6
Variable region (Fv) determinants on mouse lymphocytes.小鼠淋巴细胞上的可变区（Fv）决定簇。
Immunology. 1976 Jun;30(6):841-50.

本文引用的文献

1
FLUORESCENT BLOOD CELLS AND ANTI-FLUORESCEIN ANTIBODIES.荧光血细胞与抗荧光素抗体。
Bibl Haematol. 1964;19:578-81. doi: 10.1159/000426610.
2
Factors influencing the agglutinability of red cells. 3. Physico-chemical studies on ox red cells of different classes of agglutinability.影响红细胞凝集性的因素。3. 不同凝集性等级的牛红细胞的物理化学研究。
Vet Rec. 1967 May 6;80(18):420-8. doi: 10.1136/vr.80.18.420.
3
Rosette formation by peripheral lymphocytes.外周淋巴细胞形成玫瑰花结。
Clin Exp Immunol. 1970 May;6(5):681-8.
4
In vivo specific antigen recognition by rosette forming cells.体内玫瑰花结形成细胞对特异性抗原的识别。
Nature. 1970 Sep 19;227(5264):1251-2. doi: 10.1038/2271251a0.
5
Antigenic structure of cell surfaces. An immunoferritin study of the occurrence and topography of H-2' theta, and TL alloantigens on mouse cells.细胞表面的抗原结构。关于小鼠细胞上H-2'θ和TL同种异体抗原的出现及定位的免疫铁蛋白研究。
J Exp Med. 1969 Nov 1;130(5):979-1001. doi: 10.1084/jem.130.5.979.
6
Membrane properties of living mammalian cells as studied by enzymatic hydrolysis of fluorogenic esters.通过荧光酯的酶促水解研究活的哺乳动物细胞的膜特性。
Proc Natl Acad Sci U S A. 1966 Jan;55(1):134-41. doi: 10.1073/pnas.55.1.134.
7
A receptor for antibody on B lymphocytes. I. Method of detection and functional significance.B淋巴细胞上的抗体受体。I. 检测方法及功能意义。
J Exp Med. 1972 Mar 1;135(3):610-26. doi: 10.1084/jem.135.3.610.
8
Antigen receptors on the surface of antibody-secreting cells.抗体分泌细胞表面的抗原受体。
Nat New Biol. 1971 Oct 6;233(40):177-9. doi: 10.1038/newbio233177a0.
9
Opsonic adherence of sensitized ox red cells to human lymphocytes as measured by rosette formation.通过玫瑰花结形成测定致敏牛红细胞对人淋巴细胞的调理吞噬黏附作用。
Int Arch Allergy Appl Immunol. 1973;44(4):500-13. doi: 10.1159/000230956.
10
Variation in accessible cell surface immunoglobulin among antibody-firming cells.抗体形成细胞间可及细胞表面免疫球蛋白的变异。
J Exp Med. 1972 Jun 1;135(6):1416-22. doi: 10.1084/jem.135.6.1416.