Bouchoucha M, Jais J P, Arhan P, Landais P, Faverdin C L, Pellerin D
Laboratoire de Physiologie digestive, Hôpital Laènnec, Paris, France.
Clin Invest Med. 1994 Apr;17(2):107-14.
Pressure-relaxation curves of in vivo human rectal wall were studied in 30 normal children for 5 volumes of distension, 10-50 ml, to define the conditions of application of the quasi-linear viscoelastic law. Three normalization methods were compared: the use of the maximum pressure of the curve, the use of the first measured point after the rectal distension, and the use of the passive state defined as the inferior envelope of the experimental curve. Analysis of variance with repeated measures was used for data analysis. It was shown that: i) the first relaxation curve, corresponding to a 10-ml distension volume, was significantly different from the other curves (p < 0.0001); ii) the quasi-linear viscoelastic law could be applied to the in vivo determination of the mechanical properties of the rectal wall, when considering the mean level of the measured points; and iii) the shapes of the experimental curves at different level of distension were significantly different (p < 0.0001). We conclude that the hypothesis of quasi-linearity is appropriate, in a first approximation, as a model of rheological properties of the rectal wall.
对30名正常儿童的体内人直肠壁压力松弛曲线进行了研究，扩张体积为5种，10 - 50毫升，以确定准线性粘弹性定律的应用条件。比较了三种归一化方法：使用曲线的最大压力、使用直肠扩张后的第一个测量点以及使用定义为实验曲线下包络线的被动状态。采用重复测量方差分析进行数据分析。结果表明：i）对应于10毫升扩张体积的第一条松弛曲线与其他曲线显著不同（p < 0.0001）；ii）当考虑测量点的平均水平时，准线性粘弹性定律可应用于体内直肠壁力学性能的测定；iii）不同扩张水平下实验曲线的形状显著不同（p < 0.0001）。我们得出结论，在初步近似中，准线性假设作为直肠壁流变特性的模型是合适的。
