I-123异丁基腈肟基苯（IMP）闪烁扫描术在肝细胞癌盆腔骨转移中的潜在应用。与Ga-67闪烁扫描术的比较。

The potential use of I-123 IMP scintigraphy for pelvic bone metastases in hepatocellular carcinoma. A comparison with Ga-67 scintigraphy.

作者信息

Suto Y, Tanigawa N, Iwamiya T, Shabana M, Ohta Y

机构信息

Department of Radiology, Tottori University School of Medicine, Yonago, Japan.

出版信息

Clin Nucl Med. 1994 Apr;19(4):302-6. doi: 10.1097/00003072-199404000-00005.

DOI:10.1097/00003072-199404000-00005

PMID:8004860

Abstract

Conventional bone scintigraphy is often inconclusive in detecting bone metastases of hepatocellular carcinoma, suggesting the necessity of alternative scintigraphic agents. In this study, the diagnostic value of I-123 IMP scintigraphy was evaluated in 8 patients with 12 pelvic bone metastases from hepatocellular carcinoma, then compared with Ga-67 scintigraphy. Eleven of 12 lesions (91.7%) were detected by I-123 IMP scintigraphy; Ga-67 scintigraphy visualized 8 lesions (66.7%) in the same patient population. I-123 IMP scintigraphy is useful for detecting pelvic bone metastases of hepatocellular carcinoma with less physiologic accumulation in the intestine as compared with Ga-67 scintigraphy.

摘要

传统骨闪烁显像在检测肝细胞癌骨转移方面常常难以得出明确结论，这表明需要替代的闪烁显像剂。在本研究中，对8例患有12处骨盆骨转移的肝细胞癌患者评估了I-123 IMP闪烁显像的诊断价值，然后与Ga-67闪烁显像进行比较。I-123 IMP闪烁显像检测出了12处病变中的11处（91.7%）；在同一患者群体中，Ga-67闪烁显像显示出8处病变（66.7%）。与Ga-67闪烁显像相比，I-123 IMP闪烁显像有助于检测肝细胞癌的骨盆骨转移，且肠道生理性聚集较少。