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青少年双相情感障碍与精神分裂症的混淆:20世纪90年代的情况如何?

The confusion between bipolar disorder and schizophrenia in youth: where does it stand in the 1990s?

作者信息

Carlson G A, Fennig S, Bromet E J

机构信息

Department of Psychiatry and Behavioral Sciences, State University of New York, Stony Brook 11794-8790.

出版信息

J Am Acad Child Adolesc Psychiatry. 1994 May;33(4):453-60. doi: 10.1097/00004583-199405000-00002.

Abstract

OBJECTIVE

To determine whether the bias against diagnosing bipolar disorder in youth continues, and if so, why.

METHOD

Subjects are bipolar and schizophrenic patients taken from a county-wide sample of first admissions for psychosis. Patients are given structured interviews and consensus diagnoses at intake and 6 months. Age of onset of psychosis, gender, and 6-month consensus diagnosis between both groups are compared. To assess diagnostic bias, diagnostic stability and facility discharge diagnoses are examined in young (aged 15 through 20 years) versus adult (aged 30 through 40 years) patients.

RESULTS

Bipolar disorder and schizophrenia are diagnosed at similar rates in younger age groups by 6-month consensus. However, bipolar disorder was underdiagnosed by Suffolk County's psychiatric hospitals in the youth. The stability of both disorders in both age groups was similar and excellent. Schizophrenia had a slightly older age at first psychosis than bipolar disorder and an equal gender representation. Bipolar disorder in males was rare after age 30.

CONCLUSION

Community psychiatrists no longer call young bipolar patients schizophrenic, but they underdiagnose bipolar disorder. The more complicated nature of early-onset bipolar disorder may be a contributing factor.

摘要

目的

确定针对青少年双相情感障碍诊断的偏见是否仍然存在,若存在,原因是什么。

方法

研究对象为从全县首次因精神病入院的样本中选取的双相情感障碍和精神分裂症患者。患者在入院时和6个月时接受结构化访谈并进行一致性诊断。比较两组患者的精神病发病年龄、性别以及6个月时的一致性诊断结果。为评估诊断偏见,对年轻(15至20岁)和成年(30至40岁)患者的诊断稳定性和机构出院诊断进行检查。

结果

通过6个月时的一致性诊断,双相情感障碍和精神分裂症在较年轻年龄组中的诊断率相似。然而,萨福克县的精神病院对青少年双相情感障碍诊断不足。两种疾病在两个年龄组中的稳定性相似且良好。精神分裂症首次发病的年龄略大于双相情感障碍,且男女比例相当。30岁以后男性双相情感障碍病例罕见。

结论

社区精神科医生不再将年轻的双相情感障碍患者诊断为精神分裂症,但他们对双相情感障碍诊断不足。早发性双相情感障碍更复杂的性质可能是一个促成因素。

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