布洛芬过量服用并发肾衰竭、成人呼吸窘迫综合征和代谢性酸中毒。

Ibuprofen overdose complicated by renal failure, adult respiratory distress syndrome, and metabolic acidosis.

作者信息

Le H T, Bosse G M, Tsai Y

机构信息

University of Louisville School of Medicine, Department of Emergency Medicine, KY 40292.

出版信息

J Toxicol Clin Toxicol. 1994;32(3):315-20. doi: 10.3109/15563659409017966.

DOI:10.3109/15563659409017966

PMID:8007040

Abstract

Acute ingestion of ibuprofen commonly results in no symptoms, or minor gastrointestinal or central nervous system manifestations. While most cases of ibuprofen overdose do well, serious toxicity may occur, and is difficult to predict. A case of ibuprofen overdose is presented in which the course was complicated by metabolic acidosis, adult respiratory distress syndrome, and renal failure necessitating prolonged dialysis.

摘要

急性摄入布洛芬通常不会产生症状，或仅出现轻微的胃肠道或中枢神经系统表现。虽然大多数布洛芬过量服用的病例预后良好，但可能会发生严重毒性反应，且难以预测。本文介绍了一例布洛芬过量服用的病例，该病例的病程因代谢性酸中毒、成人呼吸窘迫综合征和肾衰竭而复杂化，需要长期透析。