Mine K, Kanazawa F, Matsumoto K, Tsuchida O, Hosoi M, Kubo C
Department of Psychosomatic Medicine, Faculty of Medicine, Kyushu University.
Nihon Rinsho. 1994 May;52(5):1329-33.
The relationships between psychiatric disorders and the symptoms of both irritable bowel syndrome (IBS) and non-ulcer dyspepsia (NUD) are herein investigated and discussed. Functional disorders of the small and large intestine induce irritable bowel syndrome. NUD is a syndrome that displays symptoms that might originate in the upper digestive system despite the absence of any organic disorder. In addition, it has also been suggested that the occurrence of NUD is based on a functional disorder of the upper digestive systems. Based on our studies of serious cases with both NUD and IBS, in approximately 50% of the NUD patients as well as about 50% of the IBS cases, a depressive disorder was found to be most closely related to the onset and continuance of the symptoms of either NUD or IBS. According to the evaluations of NUD and IBS as functional disorders and psychiatric disorders, the patients underwent treatment and all demonstrated a good response to the various treatment regimens. It is thus considered that NUD and IBS should be evaluated as both functional digestive disorders and psychiatric disorders.
本文对精神障碍与肠易激综合征（IBS）和非溃疡性消化不良（NUD）症状之间的关系进行了研究和讨论。小肠和大肠的功能紊乱会诱发肠易激综合征。非溃疡性消化不良是一种尽管没有任何器质性疾病，但仍表现出可能源于上消化系统症状的综合征。此外，也有人认为非溃疡性消化不良的发生是基于上消化系统的功能紊乱。基于我们对同时患有非溃疡性消化不良和肠易激综合征的重症病例的研究，在大约50%的非溃疡性消化不良患者以及约50%的肠易激综合征病例中，发现抑郁症与非溃疡性消化不良或肠易激综合征症状的发作和持续最为密切相关。根据对非溃疡性消化不良和肠易激综合征作为功能障碍和精神障碍的评估，患者接受了治疗，并且对各种治疗方案均表现出良好的反应。因此，认为非溃疡性消化不良和肠易激综合征应被评估为功能性消化障碍和精神障碍。
