Kovalik E C, Newman G E, Suhocki P, Knelson M, Schwab S J
Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Kidney Int. 1994 Apr;45(4):1177-81. doi: 10.1038/ki.1994.156.
Central venous stenoses are a frequent complication in hemodialysis patients. These lesions lead to fistula thromboses, arm swelling, and limit future vascular access. Stenoses are characterized by excellent initial response to transluminal angioplasty but rapid recurrence. Response to angioplasty allows classification of stenoses as elastic or nonelastic. The success of angioplasty alone in 30 patients with central venous stenoses was compared to angioplasty and Wallstent placement in 11 patients with recurrent stenoses. In those who had angioplasty alone, 7%+ failed angioplasty, 70% had > or = 50% improvement in the luminal diameter while 23% showed no improvement due to elastic lesions. Subsequently, 81% of those with a successful result restenosed at an average of 7.6 months while 100% of elastic lesions occluded in an average of 2.9 months. In the 10 patients who underwent angioplasty and Wallstent placement, 5 were due to elastic lesions with four recurrences at a mean of 8.6 months. Four of five patients (80%) stented with nonelastic lesions had reappearance of symptoms at a mean of 4.2 months. We conclude that vascular stents should be reserved for those lesions that show elastic recoil after standard angioplasty.
中心静脉狭窄是血液透析患者常见的并发症。这些病变会导致动静脉内瘘血栓形成、手臂肿胀,并限制未来的血管通路。狭窄的特点是对腔内血管成形术初始反应良好,但复发迅速。根据血管成形术的反应情况,可将狭窄分为弹性或非弹性。对30例中心静脉狭窄患者单纯血管成形术的成功率与11例复发性狭窄患者血管成形术联合Wallstent置入术的成功率进行了比较。在单纯接受血管成形术的患者中,7%血管成形术失败,70%管腔直径改善≥50%,23%因弹性病变无改善。随后,成功的患者中有81%平均在7.6个月时再次狭窄,而100%的弹性病变平均在2.9个月时闭塞。在接受血管成形术联合Wallstent置入术的10例患者中,5例是由于弹性病变,其中4例复发,平均复发时间为8.6个月。5例接受非弹性病变支架置入的患者中有4例(80%)平均在4.2个月时症状复发。我们得出结论,血管支架应保留用于标准血管成形术后出现弹性回缩的病变。