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[急性胰腺炎与生物抗氧化剂]

[Acute pancreatitis and biological antioxidants].

作者信息

Smirnov D A

出版信息

Khirurgiia (Mosk). 1994 Mar(3):30-2.

PMID:8007611
Abstract

The values of lipid free--radical oxidation and the effect of various methods of treatment on these processes were studied in 164 patients with acute pancreatitis. Combined use of oil emulsions with agents possessing antioxidation activity (unithiol, tocopherol) produced the best values. Combined therapy promoted normalization of the main parameters characterizing the activity of lipid peroxidation reactions which was attended with reduced concentrations of pancreatic enzymes and increased concentration of beta-lipoproteins in the blood. This was indicative of stabilization of the pancreatic cell membrane systems.

摘要

对164例急性胰腺炎患者的脂质自由基氧化值及各种治疗方法对这些过程的影响进行了研究。油乳剂与具有抗氧化活性的药物(二巯丙醇、生育酚)联合使用效果最佳。联合治疗促进了表征脂质过氧化反应活性的主要参数的正常化,同时伴随着血液中胰酶浓度的降低和β-脂蛋白浓度的升高。这表明胰腺细胞膜系统得到了稳定。

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