Yasuhi I, Ishimaru T, Hirai M, Yamabe T
Department of Obstetrics and Gynecology, Nagasaki University School of Medicine, Japan.
Obstet Gynecol. 1994 Jul;84(1):64-8.
To examine whether maternal meal ingestion affects fetal urine production in normal and diabetic pregnancies and whether fetal urine production is increased in diabetic pregnancy.
The hourly fetal urine production rate was measured before and after breakfast in 17 fetuses of diabetic mothers and 14 of women with normal glucose tolerance. The rate was calculated by taking serial measurements of fetal bladder volume at 2-3-minute intervals by ultrasonography.
In the control group, the hourly fetal urine production rate was significantly greater during the 2 hours after breakfast than that in the fasting state (P < .0005). In the diabetic group, the rate also tended to increase after breakfast (P = .07). In the postprandial state, the hourly fetal urine production rate was not significantly different between the groups. However, in the fasting state, it was significantly greater in the diabetic group than in the control group (P < .03).
Maternal meal ingestion should increase fetal urine production. The increased fetal urine production in the fasting state in diabetics is assumed to be one cause of hydramnios.
研究孕期进餐对正常妊娠及糖尿病妊娠胎儿尿量的影响，以及糖尿病妊娠时胎儿尿量是否增加。
对17例糖尿病母亲的胎儿及14例糖耐量正常女性的胎儿，于早餐前后测量每小时胎儿尿量生成率。通过超声以2 - 3分钟的间隔连续测量胎儿膀胱容积来计算该速率。
在对照组中，早餐后2小时每小时胎儿尿量生成率显著高于空腹状态（P <.0005）。在糖尿病组中，早餐后该速率也有增加趋势（P =.07）。餐后状态下，两组间每小时胎儿尿量生成率无显著差异。然而，在空腹状态下，糖尿病组显著高于对照组（P <.03）。
孕期进餐应会增加胎儿尿量。糖尿病患者空腹状态下胎儿尿量增加被认为是羊水过多的原因之一。
