Giovagnoni A, Ercolani P, Terilli F, Ferrara C, Paci E, Santino P
Centro RM F. Angelini, Cattedra di Radiologia, Università degli Studi di Ancona, Milano.
Radiol Med. 1994 May;87(5):636-42.
Turbo Spin-Echo (Turbo SE) pulse sequences represent a new type of fast sequences characterized by a dramatic reduction in acquisition time with similar intrinsic contrast to that of conventional Spin-Echo (SE) pulse sequences. For a preliminary clinical comparison of turbo SE and SE sequences, a consecutive series of 25 patients with focal liver lesions was investigated by means of MRI at 1.0 T. The patients were selected on the basis of US or CT positive liver scans for focal lesions. All patients underwent MRI following the same protocol: axial T1-weighted (T1W) gradient echo (GE) sequences (TR/TE = 110/6 ms) with the "breath-hold" technique, T2-weighted (T2W) SE sequences (TR/TE = 1730/90 ms; FL = 60, M = 128 x 256, 2 AC, TA = 7 min 26 sec) and turbo SE sequences (TR/TE = 5100/112 ms, M = 240 x 256, 2 AC, TA = 2 min 48 sec). Slice thickness was 10 mm with a 1-mm gap in all cases. Qualitative (number, size and definition of the lesions) and quantitative (contrast-to-noise ratio (CNR) and relative CNR) variables were considered. SE and turbo SE sequences demonstrated the same number of lesions; the smallest lesion (3 mm) was identified by turbo SE sequences. Turbo SE sequences better depicted lesion margins than SE sequences. In all cystic conditions, CNR was higher in turbo SE than in SE sequences, while it was lower in all the extant conditions. This preliminary experience proves turbo SE pulse sequences to be a valuable tool in liver MRI, which calls for further clinical trials.
快速自旋回波（Turbo SE）脉冲序列是一种新型的快速序列，其特点是采集时间显著缩短，而内在对比度与传统自旋回波（SE）脉冲序列相似。为了对Turbo SE和SE序列进行初步临床比较，我们对连续25例有肝脏局灶性病变的患者进行了1.0 T的MRI检查。这些患者是根据超声或CT肝脏扫描发现局灶性病变阳性而入选的。所有患者均按照相同方案进行MRI检查：采用“屏气”技术的轴向T1加权（T1W）梯度回波（GE）序列（TR/TE = 110/6 ms）、T2加权（T2W）SE序列（TR/TE = 1730/90 ms；层厚 = 60，矩阵 = 128 x 256，采集2次，扫描时间TA = 7分26秒）和Turbo SE序列（TR/TE = 5100/112 ms，矩阵 = 240 x 256，采集2次，扫描时间TA = 2分48秒）。所有病例的层厚均为10 mm，层间距为1 mm。考虑了定性（病变的数量、大小和清晰度）和定量（对比噪声比（CNR）和相对CNR）变量。SE和Turbo SE序列显示的病变数量相同；Turbo SE序列识别出了最小的病变（3 mm）。Turbo SE序列比SE序列能更好地显示病变边缘。在所有囊性病变中，Turbo SE序列的CNR高于SE序列，而在所有实性病变中则较低。这一初步经验证明Turbo SE脉冲序列是肝脏MRI中的一种有价值的工具，需要进一步进行临床试验。
