Merino Muñoz D, Márquez P, Ollero Baturone M, Alcoucer Díaz R, Gimeno A, Martín Suárez I, Pujol de la Llave E
Servicio de Medicina Interna, Hospital Manuel Lois, Huelva.
Rev Clin Esp. 1994 Feb;194(2):104-6.
The epidemiology of retrovirus HTLV-II is scarcely known even though it appears to be narrowly related to parenteral drug addiction. In order to find out the prevalence of HTLV-II among IVDU in our area, the sera of 137 subjects who came to our center for clinical evaluation were analyzed. The presence of HTLV-I/II antibodies were determined via ELISA and the sera that were repeatedly reactive were confirmed by the Western blot technique which reveals infection by both retroviruses. Two sera were repeatedly positive by ELISA (1.45 percent). Western blot confirmed HTLV-II positivity in both sera. Serology for HIV-1 was positive in 52 sera (37.9%). The two HTLV-II positive sera were also positive for HIV-1. These results indicate that HTLV-II infection is already present in the IVDU population in our area, where, similar to what happens in the U.S. and Europe, this retrovirus is implicated in the majority of HTLV infections in IVDU.
尽管逆转录病毒HTLV-II似乎与注射吸毒密切相关，但其流行病学情况却鲜为人知。为了了解我们地区注射吸毒者中HTLV-II的流行情况，我们分析了137名到我们中心进行临床评估的受试者的血清。通过酶联免疫吸附测定法（ELISA）检测HTLV-I/II抗体的存在，并通过蛋白质印迹技术对反复呈阳性反应的血清进行确认，该技术可揭示两种逆转录病毒的感染情况。ELISA检测中有两份血清反复呈阳性（1.45%）。蛋白质印迹法确认这两份血清中HTLV-II均为阳性。52份血清（37.9%）的HIV-1血清学检测呈阳性。两份HTLV-II阳性血清的HIV-1检测也呈阳性。这些结果表明，我们地区的注射吸毒人群中已经存在HTLV-II感染，在美国和欧洲也有类似情况，在这些地区，这种逆转录病毒与注射吸毒者中大多数HTLV感染有关。
